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Ivomec PourON Print E-mail
Written by Administrator-GL   
Friday, 13 March 2009

IVOMEC® POUR-ON FOR CATTLE
Ivermectin Pour-On for Cattle
NOTE from Administrator: This is a cattle product but is commonly used on goats as Off Label- we use it at the rate of 1cc/20lbs in a syringe with no needle dribbles along the back line from neck to tail- directly on the skin for the control and effective removal of Biting lice and other external parasites. Even though this is also a dewormer, it is not effective as a dewormer on goats- Only as an external parasite control- you still need to deworm your goats for internal parasites. Ivermectin pour-on is the only effective parasite control I have seen that effectively rids the goat of Biting lice- This is equal to Ivomec PourOn.

Added Note: Ivomec injectable for cattle is effective against lice for Cattle but not for goats, they have a different  metabolism therefore  the injectable  will not kill lice on goats - therefore the pour on is needed for lice removal.


For BABY GOATS: I use a cotton ball with some of the Ivermectin on it not dripping wet, rub onto skin in a few places on the spine and if the lice are severe a bit (using the same damp cotton ball) on the inner groin area.


 

Merial
 
(ivermectin)

Contains 5 mg ivermectin/mL
Parasiticide

Consult your veterinarian for assistance in the diagnosis, treatment and control of parasitism.

INTRODUCTION
IVOMEC (ivermectin) Pour-On delivers internal and external parasite control in one convenient low-volume application. Discovered and developed by scientists from Merck Research Laboratories, IVOMEC Pour-On contains ivermectin, a unique chemical entity.Ivomec Pour On
Ivomec Pour On

MODE OF ACTION
Ivermectin is a member of the macrocylic lactone class of endectocides which have a unique mode of action. Compounds of the class bind selectively and with high affinity to glutamate-gated chloride ion channels which occur in invertebrate nerve and muscle cells.

This leads to an increase in the permeability of the cell membrane to chloride ions with hyperpolarization of the nerve or muscle cell, resulting in paralysis and death of the parasite.  Compounds of this class may also interact with other ligand-gated chloride channels, such as those gated by the neurotransmitter gamma-aminobutyric acid (GABA).

The margin of safety for compounds of this class is attributable to the fact that mammals do not have glutamate-gated chloride channels, the macrocyclic lactones have a low affinity for other mammalian ligand-gated chloride channels and they do not readily cross the blood-brain barrier.

INDICATIONS
IVOMEC Pour-On applies at the recommended dose level of 500 mcg/kg is indicated for the effective control of these parasites.

Gastrointestinal Roundworms
Ostertagia ostertagi (including inhibited stage) (adults and L4), Haemonchus placei (adults and L4), Trichostrongylus axei (adults and L4), T. colubrifomis:  (adults and L4), Cooperia oncophora (adults and L4), Cooperia punctata:  (adults and L4), Cooperia surnabada (adults and L4), Strongyloides papillosus (adults), Oesophagostomum radiatum (adults and L4), Trichuris spp. (adults).

Lungworms
Dictyocaulus viviparus (adults and L4)

Cattle Grubs
Hypoderma bovis, H. lineatum

Mites
Sarcoptes scabiei var. bovis

Lice
Linognathus vituli, Haematophinus eurysternus, Damalinia bovis, Solenopotes capillatus

Horn Flies
Haematobia irritans

Persistent Activity
IVOMEC Pour-On has been proved to effectively control infections and to protect cattle from re-infection with Ostertagia ostertagi, Oesophagostomum radiatum, Haemonchus placei, Trichostrongylus axei, Cooperia punctata and Cooperia oncophora for 14 days after treatment.

Treatment of Cattle for Horn Flies
IVOMEC Pour-On controls horn flies (Haematobia irritans) for up to 28 days after dosing.  For best results IVOMEC Pour-On should be part of a parasite control program for both internal and external parasites based on the epidemiology of these parasites.  Consult your veterinarian or an entomologist for the most effective timing of applications.

Dosage
The does rate is 1 ml for each 22 lb of body weight.  The formulation should be applied along the topline in a narrow strip extending from the withers to the tailhead.

Administration
Squeeze-Measure-Pour System (8.5 fl oz/250 ml Bottle with 25 ml Metering Cup)
Attach the metering cup to the bottle.
Set the does by turning the top section of the cup to align the correct body weight with the pointer on the knurled cap.  When the body weight is between markings, use the higher setting.
Hold the bottle upright and squeeze it to deliver a slight excess of the required dose as indicated by the calibration lines.
By releasing the pressure, the dose automatically adjusts to the correct level. Tilt the bottle to deliver the dose. The off (STOP) position will close the system between dosing.

Squeeze-Measure-Pour System (33.8 fl oz/1 Liter Bottle with 50 ml Metering Cup)
Attach the metering cup to the bottle.
Set the dose by turning the top section of the cup to align the correct body weight with the pointer on the knurled cap. When body weight is between markings, use the higher setting.
Hold the bottle upright and squeeze it to deliver a slight excess of the required dose as indicated by the calibration lines.
By releasing the pressure, the dose automatically adjusts to the correct level.  Tilt the bottle to deliver the dose.  When 220 lb (10 ml) or 330 lb (15 ml) dose is required, turn the pointer to "STOP" before delivering the dose.  The off (STOP) position will close the system between dosing.

Collapsible Pack (84.5 fl oz/2.5 L Pack and 169 fl oz/5 L Pack)
Connect the applicator gun to the collapsible pack as follows:
Attach the open end of the draw-off tubing to the dosing equipment.  (Because the solvents used in the formulation, only the Protector Drench Gun from Instrument Supplies Limited, or equivalent, is recommended.  Other applicators may exhibit compatibility problems resulting in locking, incorrect dosage or leakage.)
Replace the shipping cap with the draw-off cap and tighten down.  Attach draw-off tubing to the draw-off cap.
Gently prime the applicator gun, checking for leaks.
Follow the manufacturer's directions for adjusting the dose.
When the interval between uses of the applicator gun is expected to exceed 12 hours, disconnect the gun and draw-off tubing from the product container and empty the product from the gun and tubing back into the product container.  To prevent removal of special lubricants from the Protector Drench Gun, the gun and tubing must not be washed.

20 Liter Pack (676 fl oz/20 L Pack)
Use dosing equipment (applicator, draw-off tubing, cap with stem) compatible with IVOMEC® (ivermectin) Pour-On.  Other dosing equipment may be incompatible, resulting in locking, incorrect dosage and leakage.  Follow the dosing equipment manufacture's directions for adjusting the dose and proper use and maintenance of the dosing equipment.  Connect the dosing applicator and the draw-off tubing to the container as follows:
Attach the open end of the draw-off tubing to an appropriate dosing applicator.  Attach draw-off tubing to the cap with the stem.  Replace the shipping cap with the cap having the draw-off tubing.  Gently prime the dosing applicator, checking for leaks.
When the interval between uses of the applicator gun is expected to exceed 12 hours, disconnect the gun, draw-off tubing and cap with stem from the product container, empty the product from the gun and tubing back into the product container and replace the shipping cap.

ANIMAL SAFETY
Studies conducted in the U.S.A. have demonstrated the safety margin for ivermectin.  Based on plasma levels, the topically applied formulation is expected to be at least as well tolerated by breeding animals as is the subcutaneous formulation which had no effect on breeding performance.

WARNING
NOT FOR USE IN HUMANS.

Keep this and all drugs out of the reach of children.

The Material safety Data Sheet (MSDS) contains more detailed
occupational safety information. To report adverse effects, obtain an
MSDS or for assistance, contact Merial at 1-888-637-4251.

WARNING!  FLAMMABLE!
KEEP AWAY FROM HEAT, SPARKS, OPEN FLAME, AND OTHER SOURCES OF IGNITION.

This product should not be applied to self or others because it may be irritating to human skin and eyes and absorbed through the skin.  To minimize accidental skin contact, the user should wear a long-sleeved shirt and rubber gloves.  If accidental skin contact occurs, wash immediately with soap and water.  If accidental eye exposure occurs, flush eyes immediately with water and seek medical attention

.

RESIDUE INFORMATION: Cattle must not be treated within 48 days of slaughter for human consumption.  Because a withdrawal time in milk has not been established, do not use in female dairy cattle of breeding age.  A withdrawal period has not been established for this product in pre-ruminating calves.  Do not use in calves to be processed for veal.

PRECAUTIONS
Store away from excessive heat (104°F/40°C) and protect from light.

Use only in well-ventilated areas or outdoors.
Close container tightly when not in use.
Cattle should not be treated when hair or hide is wet since reduced efficacy may be experienced.
Do not use when rain is expected to wet cattle within six hours after treatment.
This product is for application to skin surface only.  Do not give orally or parenterally.
Cloudiness in the formulation may occur when IVOMEC Pour-On is stored at temperatures below 32°F.  Allowing to warm at room temperature will restore the normal appearance without affecting efficacy.
Antiparasitic activity of ivermectin will be impaired if the formulation is applied to areas of the skin with mange scabs or lesions, or with dermatoses or adherent materials, e.g., caked mud or manure.
Ivermectin has been associated with adverse reactions in sensitive dogs; therefore, IVOMEC Pour-On is not recommended for use in species other than cattle.

When to Treat Cattle with Grubs
IVOMEC Pour-On effectively controls all stages of cattle grubs.  However, proper timing of treatment is important.  For the most effective results, cattle should be treated as soon as possible after the end of the heel fly (warble fly) season.  While this is not peculiar to ivermectin, destruction of Hypoderma larvae (cattle grubs) at the period when these grubs are in vital areas may cause undesirable host-parasite reactions.  Killing Hypoderma lineatum when it is in the esophageal tissues may cause bloat; killing H. bovis  when it is in the vertebral canal may cause staggering or paralysis.  Cattle should be treated either before or after these stages of grub development.

Cattle treated with IVOMEC Pour-On at the end of the fly season may be re-treated with IVOMEC during the winter without danger of grub-related reactions.  For further information and advice on a planned parasite control program, consult your veterinarian.

Environmental Safety
Studies indicate that when ivermectin comes in contact with soil it readily and tightly binds to the soil and becomes inactive.  Free ivermectin may adversely affect fish and certain aquatic organisms.  Do not contaminate water by direct application or by improper disposal of drug containers.  Dispose of containers in an approved landfill or by incineration.

As with other avermectins, ivermectin is excreted in the dung of treated animals and can inhibit the reproduction and growth of pest and beneficial insects that use dung as a source of food and for reproduction.  The magnitude and duration of such effects are species and life-cycle specific.  When used according to label directions, the product is not expected to have an adverse impact on populations of dung-dependent insects.

HOW SUPPLIED
IVOMEC Pour-On is available in an 8.5 fl oz/250 ml bottle or 33.8 fl oz/1 l bottle with a squeeze-measure-pour system, or in an 84.5 fl oz/2.5 L or 169 oz/5 L collapsible pack, or 676 fl oz/20 L container intended for use with appropriate automatic dosing equipment.

MERIAL LTD.
3239 SATELLITE BLVD.
DULUTH, GA 30096
1-88-637-4251

www.merial.com
 

Last Updated ( Monday, 21 February 2011 )
 
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